Health care information for sinusitis sufferers

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Aminoglycosides
Aminoglycosides are used intravenously (IV), by injection (IM), or topically to treat serious bacterial infections in many different parts of the body. They work by killing bacteria or preventing their growth. Some aminoglycosides may be given by irrigation (applying a solution of the medicine to the skin or mucus membranes or washing out a body cavity) or by inhalation into the lungs or nose. Used in this way, they are effective against nose and sinus infections caused by a particularly dangerous kind of bacteria, gram-negative pseudomonas. Aminoglycosides may be combined with one or more other medicines to treat bacterial infections, or used alone. They are prescribed for the most serious and difficult-to-treat infections, including pseudomonas and other severe gram-negative infections.

Aminoglycosides should be administered only by or under the immediate supervision of a physician. Because they have potentially serious side effects, including damage to hearing, sense of balance, and kidneys, they are prescribed only for bacterial infections that may not respond to other medicines. The risk of side effects is higher for elderly patients and newborn infants. Your doctor should discuss the risks as well as the advantages of these medicines with you before administering them. Close monitoring of blood levels is necessary when aminoglycosides are administered by an IV.

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Version 2.0 This web page was first published on April 30, 2002, and was last updated on June 14, 2006.
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